Azelaico acid

3.38

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Azelaic Acid

INCI: Acelaic Acid.

CAS N.: 123-99-9
EC: 204-669-1

Molecular Formula: C9H16O4
Molecular Weight: 188.22
COLOR 440 nm (TRANSMITANCE) => 80%
COLOR 550 nm (TRANSMITANCE) => 90%
ACIDITY INDEX 585.00-610.00 mgKOH
WEALTH (Azelaic Ac.) => 98%
HUMIDITY =< 0.30 %
MELTING POINT 102 - 110ºC

Incompatibilities: Carbopol type gels, non-ionic emulsions.
Observations: It is oxidizable.
Precautions: Avoid contact with the nasal, oral, and ocular mucosa. It is recommended to limit simultaneous use with aggressive cosmetics as much as possible. If persistent irritation appears, reduce the frequency of application or discontinue treatment.
Side effects: At the beginning of treatment, itching and local irritation may occur, as well as exceptionally hypopigmentation and photosensitization.
Contraindications: Pregnancy and lactation.
Conservation: In tightly closed containers. PROTECT FROM LIGHT. Easily oxidizable.


What is azelaic acid used for?

Azelaic acid is a skin care ingredient used in cosmetics for its various beneficial properties. It is a dicarboxylic acid derived from cereals such as wheat, barley and rye. Azelaic acid is known for its ability to exfoliate the skin, unclog pores, and reduce keratin production, making it effective in treating acne and improving skin texture. In addition, it has anti-inflammatory and antioxidant properties, helping to reduce redness and hyperpigmentation. Its appearance is usually that of a white powder and its chemical formula is C 9 H 16 O 4 . Azelaic acid is commonly found in creams, serums, and spot treatments, and addresses different skin concerns and promotes a clearer, more even complexion.

What is azelaic acid used for?

Azelaic acid finds versatile uses in skin care, hair care, and cosmetics due to its numerous beneficial properties.

  • Skin care: It is mainly used to treat acne and rosacea. It helps exfoliate the skin, unclog pores and reduce the proliferation of acne-causing bacteria. It also has anti-inflammatory properties that calm the redness and irritation associated with rosacea.
  • Hair Care – Used to treat conditions such as dandruff and scalp inflammation in hair care products. Its antifungal and anti-inflammatory properties help fight dandruff-causing fungi and soothe irritated scalp. By regulating sebum production, it also contributes to maintaining a healthier scalp environment, promoting overall hair health and reducing flaking.
  • Cosmetic products: In cosmetics, azelaic acid's ability to even out skin tone and reduce the appearance of hyperpigmentation makes it a popular ingredient in foundations, concealers, and BB creams. Its exfoliating properties improve the effectiveness of chemical exfoliants in various skin care formulations, resulting in smoother, more radiant skin.

Origin

Azelaic acid is produced through a chemical reaction called ozonolysis, which involves the reaction of oleic acid with ozone (O 3 ) in the presence of a catalyst. Oleic acid is a monounsaturated fatty acid found in various vegetable oils such as olive oil. During the ozonolysis process, ozone molecules break the double bond of the oleic acid molecule, resulting in the formation of azelaic acid.

Azelaic acid is generally considered safe for topical use in skin care and cosmetics when used as directed and within recommended concentrations. It is well tolerated by most people, with minimal reports of adverse reactions. However, patch testing is recommended for people with sensitive skin to ensure compatibility and avoid potential irritation.

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