Nº CAS: 303-98-0
Nº EINECS: 206-147-9
Synonyms: ubiquinone Ubiquinone 10. 50. Coenzyme Q10.
Molecular Formula: C59H90O4
Molecular Weight: 863.34
Physical-Chemical Data: yellow or orange crystalline powder. Practically insoluble in water, soluble in acetone, slightly soluble in anhydrous ethanol.
Properties and uses:
Ubidecarenone is a coenzyme that is naturally in the respiratory chain, which is related to electron transport in the mitochondria, and possibly also involved in the metabolism of heart muscle. It is believed that makes a free radical scavenging action, an antioxidant and stabilizer developing action of the properties of membranes.
Topically it is used for its antioxidant properties (free radical scavenger) mainly in formulations to prevent aging and damage caused by solar radiation on the skin. Its antioxidant effectiveness seems superior to other molecules such as vitamin E. Topical application of ubidecarenone antieritematógeno produces a powerful effect than indomethacin, which is considered capable of reducing free radical formation.
It is also important to note that possesses the ability to inhibit the enzymatic activity of ornithine decarboxylase (ODC), which is the ability to curb excessive keratinocyte proliferation which occurs as a result of solar battery and causes an unsightly hyperkeratosis .
Orally it is used as an antioxidant and free radical scavenger in mild to moderate congestive heart failure in combination with standard treatment, degenerative diseases, and as immune system stimulant.
It has also been used orally in conditions associated with deficiencies of coenzyme.
Finally it investigated for use for the treatment of Huntington's chorea. Ubidecarenone orally is often used in combination with selenium and vitamins C and E.
Dosage: Topically, typically 0.1 - 0,5%.
Observations: It is photosensitive. Incorporate cold formulations.
Storage: In airtight containers. PROTECT FROM LIGHT.